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I. M. Le-Deygen, E. V. Kudryashova

PEG-chitosan as a perspective stabilizing agent for liposomal suspension: molecular weight and pegylation degree influence on the physico-chemical properties of the complex

Abstract

The possibility of regulation of physico-chemical properties (stability, size, binding sites) of liposomal containers for drug delivery by selection of molecular weight and the degree of modification of PEG-chitosan has been demonstrated. The effect of the regulation of the release of doxorubicin from liposomal containers depending on the properties of the polymer and pH was demonstrated.
Key words: doxorubicin, liposomes, chitosan, FTIR.
Moscow University Chemistry Bulletin.
2018, Vol. 59, No. 2, P. 151
   

Copyright (C) Chemistry Dept., Moscow State University, 2002
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