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I. M. Deygen, E. V. Kudryashova
Influences of glycol-chitosan on
functional and structural properties of anionic liposomes
Abstract
In present paper it was demonstrated, that
one could apply derivatives of chitosan, namely, glycol-chitosan, in order to
produce liposomal containers for doxorubicin. Kdis of anionic
liposomes–glycol-chitosan complexes were evaluated by FTIR as 3,5·10–4
M and 1·10–5 M, depending on the phase state of liposomes.
Significant influence of complex formation on doxorubicin release was found.
Key words: doxorubicin, liposomes,
chitosan, FTIR.
Copyright (C) Chemistry Dept., Moscow State University, 2002
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