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I. M. Deygen, E. V. Kudryashova

Influences of glycol-chitosan on functional and structural properties of anionic liposomes


In present paper it was demonstrated, that one could apply derivatives of chitosan, namely, glycol-chitosan, in order to produce liposomal containers for doxorubicin. Kdis of anionic liposomes–glycol-chitosan complexes were evaluated by FTIR as 3,5·10–4 M and 1·10–5 M, depending on the phase state of liposomes. Significant influence of complex formation on doxorubicin release was found.
Key words: doxorubicin, liposomes, chitosan, FTIR.
Moscow University Chemistry Bulletin.
2016, Vol. 57, No. 3, P. 154

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