K. M. Marakulina, R. V. Kramor, Yu. K. Lukanina, M. V. Kozlov, L. N. Shishkina.
Use of the
UV- and IR-spectroscopy for investigation of complexation between molecules of
sphingomyelin and phenolic antioxidants
method of isomolar series was adapted for investigation of phenomenon and
stoichiometry of complexation of sphingomyelin with phenolic antioxidants
(isobornyl phenols with different structure and ionol). The sphingomyelin is
shown to react with phenolic antioxidants at the different molar ratio, which
depends on the structure of the phenols. Analysis of changes in the IR-spectra
of mixtures with respect to the spectra of individual components revealed that
the hydroxyl group of phenolic antioxidants, hydroxyl, ester amide linkage and
choline groups of sphingomyelin are involved in the formation of complex.
Key words: complexation,
method of isomolar series, sphingomyelin, isobornylphenols, ionol.
Copyright (C) Chemistry Dept., Moscow State University, 2002