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E. V. Nurieva, O. N. Zefirova, V. N. Nuriev, N. V. Zyk, D. G. Weiss, S. A. Kuznetsov, N. S. Zefirov

Synthesis of compounds with potential antitumour activity. V. (2R,3S)-N-Benzoylphenylisoserine esters with substituted bicyclo[3.3.1]nonanes

Abstract

Four (2R,3S)-N-benzoylphenylisoserine esters with substituted bicyclo[3.3.1]nonanes were synthesized. The compounds were found to be unable to promote tubulin polymerization, but caused a weak tubulin aggregation (oligomerization).
Moscow University Chemistry Bulletin.
2009, Vol. 50, No. 4, P. 273
   

Copyright (C) Chemistry Dept., Moscow State University, 2002
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