A. L. Nikolaev, A. V. Gopin, D. S. Chicherin, V. E. Bozhevolnov, I. V. Melikhov
Localization of acoustic energy in gel systems on solid-phase
Comparative investigation of thermal effects of ultrasound action on
agarous gel containing iron (III) hydroxide and barium sulfate nanoparticles
was performed. Differences in interaction of iron (III) hydroxide and barium
sulfate with agarose matrix were established. Relative changes in ultrasound
adsorption due to modifier particles present in a gel were estimated. It was
shown that systems with modifiers localized on separate elements of matrix
volume possess higher thermal effects. Production of "containers"
with ultrasound-controlled drug release on the basis of thermosensitive gels
containing solid phase inclusions was discussed as an example of possible
application of the effects described.
Copyright (C) Chemistry Dept., Moscow State University, 2002