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S. V. Averkiev, N. Yu. Ignat’yeva, Ye. N. Sobol’, A. B. Shekhter, S. A. Baranov, M. V. Obrezkova, V. V. Lunin
Collagen fibre
modification under laser treatment of the cartilage
Abstract
An
integrated study of the cartilage treated by IR laser radiation was carried out
in this work. Thermal stability of the collagen fibres was studied by
Differential Scanning Calorimetry, steadiness of the cartilage samples to the
trypsin digestion was defined and comparison investigation of the cartilage’
morphological properties was done. It was shown that after 60 sec of the laser
irradiation of the cartilage at 70°C only partial denaturation (дo 16%) of the collagen type II took place. Laser treatment
results in a collagen fibres modification leading to the decrease of the
enthalpy of the collagen denaturation and to the weakening of his tinctorial
properties.
Copyright (C) Chemistry Dept., Moscow State University, 2002
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